Soil bacteria could be used to deliver cancer drugs

Researchers have found a way to inject the Clostridium sporogenes bacterium into patients, where it grows inside solid tumors. It then interacts with a separate drug injected into the cancer sufferers, destroying the cancer cells while preserving the healthy ones in what could be a more precise treatment than surgery.

An anti-cancer drug is then injected into the patient in an inactive form, and is then activated by the bacteria’s enzyme, destroying the tumour cells in the vicinity. The technique has recently been improved by the team introducing a “much-improved” version of the enzyme into the DNA of the soil bacteria, which can be produced in greater quantities in the tumor. Read more…

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