Age at Cancer Diagnosis Among Persons With AIDS

It is recently illustrated that naively comparing the ages at cancer diagnosis between persons with AIDS and the general population is inappropriate because the age distributions of the populations at risk differ. After adjustment for these population differences, it is  found that persons with AIDS do not develop most types of cancer at younger ages than the general population.

Although other investigators have suggested that elevated cancer risk at all ages could be evidence of accelerated aging , it is  posited that accelerated aging requires particularly elevated cancer risk at young ages, which would lead to a downward shift in the age distribution of cancer diagnoses. If HIV caused premature aging, we would expect both diagnosis of cancer at earlier ages and broadly increased cancer risk, particularly for types of cancer commonly associated with aging (for example, cancer of the prostate, colorectum, and breast), which has not been observed . It is  therefore argue that cancer should not be included as part of a general syndrome of HIV-associated accelerated aging. Read more…

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s


%d bloggers like this: