Womb cancer genome scan reveals prostate cancer link

The first genome scan for womb cancer has revealed a genetic region that is associated with a reduced risk of the disease. The same region, called HNF1B, has been linked previously to lower prostate cancer risk in men.The findings offer a tantalizing hint that there may be shared mechanisms of disease that have not been recognized previously.

Women with the protective ‘version’ of the gene are on average 15-18 per cent less likely to develop womb cancer, and men with the same version are 21 per cent less likely to develop prostate cancer. However, the same gene has also been linked to a 10-14 per cent greater risk of developing type 2 diabetes. Read more…

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