Breakthrough in breast cancer research

The enzyme lysyl oxidase-like 2 (LOXL2) is needed for tumour cells to escape from the breast and invade surrounding tissue, thereby allowing cancer cells to travel to distant organs. Using laboratory models, the team showed that blocking the function of LOXL2 significantly decreased the spread of the cancer from the breast to the lungs, liver and bone.
Study suggests that drugs which block this enzyme may be effective in preventing patients’ cancer from spreading,” lead researcher Dr Janine Erler said. In Britain alone, around 12,000 women die from breast cancer each year, mostly because their cancer has spread to other parts of their body. In 2008, 47,693 women were diagnosed with breast cancer. Read more…

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