Archive for January, 2011

Immunosuppressives Could Become Anti-Cancer Agents

January 31, 2011

Immunosuppressives seem to hold exciting promise in cancer treatment. One particular antibiotic could become an anti-cancer agent too, it is hoped.
Immunosuppressive drugs can form a part of treatment of autoimmune diseases like rheumatoid arthritis, lupus or HIV, which arise from inappropriate immune responses. In such instances, the body’s immune system attacks the body, instead of attacking foreign cells. It is to inhibit such a response, the immunosuppressives are pressed into service. Such drugs are also used in organ transplant. Read more…


New test predicts cancer relapse

January 29, 2011

A new, highly accurate genetic test that can predict whether some women with breast cancer will suffer a relapse is discovered.
The test is reported to be superior than an existing test, and has the potential to spare women at a very low risk of relapse of breast cancer from undergoing toxic chemotherapy.
ncreasingly, oncologists are zeroing in on the genetic underpinnings of cancer. For breast cancer, that means testing for things like the HER2/neu gene, and consequently tailoring a drug therapy like Herception for that type of disease. Read more…

New treatment for ovarian cancer.

January 28, 2011

A device that filters free floating cancer cells from the body could mean a new treatment option for ovarian cancer.
The device provides a way to extend lives of patients with ovarian cancer while continuing other treatments. The machine that is used outside of the body lowers the chances that a patient will develop secondary tumors that can complicate cancer treatment.
One can remove the primary cancer, but the problem is metastasis. A good deal of the metastasis in ovarian cancer comes from cancer cells sloughing off into the abdominal cavity and spreading the disease that way. Read more…

“Rogue gene” may stop cancer spread

January 27, 2011

It is discovered a “rogue gene” which helps cancer spread around the body and blocking it with the right kind of drugs could stop many types of the disease in their tracks.
The challenge now is to identify a potent drug that will get inside cancer cells and destroy the activity of the rogue gene. Read more…

Fight Cancer With Cancer Cells

January 25, 2011

In an audacious twist on the concept of fighting fire with fire, scientists have developed a provocative strategy of fighting cancer with cancer.
Researchers are taking tumor cells from mice, encapsulating them in beads made from a seaweed-derived sugar called agarose, and implanting them in the abdomen of cancer patients. There, cells in the beads secrete proteins researchers believe could signal a patient’s cancer to stop growing, shrink or even die. Read more…

Novel peptide ‘kills’ cancer cells more effective than current therapies

January 24, 2011

Scientists have discovered a novel peptide that can act as a potent inducer of cancer cell death, which may have significant implications for therapeutic agents used to treat cancer.

Researchers suggested that the amphipathic tail-anchoring peptide, or ATAP, might provide more successful outcomes in cancer treatment than the BH3 peptide-based therapy currently used. Read more…

Pill to combat skin cancer

January 21, 2011

In what could revolutionise the treatment for malignant melanoma, scientists have developed a new pill which they say significantly improves survival rates of patients suffering from the deadliest form of skin cancer.
Researchers behind the drug, known as RG7204, claimed that it was found to reduce the size of tumours by 80% in patients.And the side effects such as rashes and photosensitivity were all classified as mild.
Read more…

Mutated Gene Found in Patients with Renal Cancer

January 20, 2011

Renal cancer is among the 10 most common cancers in both men and women.Renal Cell Carcinoma (RCC) accounts for 90% of kidney cancer cases with clear cell RCC (ccRCC) being the most prevalent subtype. Researchers have found a genetic mutation that occurs in one in three patients with this type of cancer, a finding that is critical to finding treatment for the disease.
Team of researchers previously identified the role of the VHL gene and SETD2 in an inherited form of kidney cancer known as sporadic renal cell carcinoma. These three genes are all involved in altering the chromatin structure that holds DNA together and their location allows cancer to reduce the number of genetic events needed to hit and inactivate all three genes. Read more…

Nanoparticle blocks key molecule involved in spread of breast cancer

January 19, 2011

Ongoing clinical trials have shown that a peptide known as PHSCN can slow or prevent the spread of metastatic breast cancer in over a third of patients treated with the drug. This drug works by binding to an activated receptor found on the surface of breast tumor cells but not normal cells. Read more…

Drive for early cancer detection, free chemotherapy

January 18, 2011

India is going all out against cancer — the non-communicable disease (NCD) that affects 10 lakh new Indians every year and kills four lakh.
The Union health ministry is launching a national programme, which will not only help diagnose cancer cases early among the general population but also provide chemotherapy free of cost. At present, the two biggest problems with cancer control are that the majority of the cases are diagnosed in the last stage while those who are diagnosed can’t afford the high costs of treatment in form of chemotherapy and radiotherapy. Read more…